You should play most hands heads up(unlike a multi-player table). If you have a sizeable chip lead, you should bet hard when you have a good starting hand. Get all the cheap looks at the flop that you can. Let it go to the river before going all in when you've flopped a monster, you're not likely to get a call from a good opponent in this situation. If your opponent goes all in after the flop, fold unless you have good potential. Steal blinds when you have semi-good hole cards.